Evolution of surface and nonstructural-1 genes of influenza B viruses isolated in the Province of Québec, Canada, during the 1998-2001 period.
Identifieur interne : 000946 ( Main/Exploration ); précédent : 000945; suivant : 000947Evolution of surface and nonstructural-1 genes of influenza B viruses isolated in the Province of Québec, Canada, during the 1998-2001 period.
Auteurs : Yacine Abed [Canada] ; Michael B. Coulthart ; Yan Li ; Guy BoivinSource :
- Virus genes [ 0920-8569 ] ; 2003.
Descripteurs français
- KwdFr :
- Analyse de séquence, Antigènes viraux (), Antigènes viraux (génétique), Données de séquences moléculaires, Glycoprotéine hémagglutinine du virus influenza (), Glycoprotéine hémagglutinine du virus influenza (génétique), Glycoprotéine hémagglutinine du virus influenza (immunologie), Grippe humaine (virologie), Grippe humaine (épidémiologie), Humains, Mutation faux-sens, Phylogénie, Protéines virales non structurales (), Protéines virales non structurales (génétique), Québec (épidémiologie), Sialidase (), Sialidase (génétique), Similitude de séquences, Tests d'inhibition de l'hémagglutination, Variation des antigènes (génétique), Virus influenza B (génétique), Virus influenza B (immunologie), Virus influenza B (isolement et purification), Évolution moléculaire.
- MESH :
- génétique : Antigènes viraux, Glycoprotéine hémagglutinine du virus influenza, Protéines virales non structurales, Sialidase, Variation des antigènes, Virus influenza B.
- immunologie : Glycoprotéine hémagglutinine du virus influenza, Virus influenza B.
- isolement et purification : Virus influenza B.
- virologie : Grippe humaine.
- épidémiologie : Grippe humaine, Québec.
- Analyse de séquence, Antigènes viraux, Données de séquences moléculaires, Glycoprotéine hémagglutinine du virus influenza, Humains, Mutation faux-sens, Phylogénie, Protéines virales non structurales, Sialidase, Similitude de séquences, Tests d'inhibition de l'hémagglutination, Évolution moléculaire.
English descriptors
- KwdEn :
- Antigenic Variation (genetics), Antigens, Viral (chemistry), Antigens, Viral (genetics), Evolution, Molecular, Hemagglutination Inhibition Tests, Hemagglutinin Glycoproteins, Influenza Virus (chemistry), Hemagglutinin Glycoproteins, Influenza Virus (genetics), Hemagglutinin Glycoproteins, Influenza Virus (immunology), Humans, Influenza B virus (genetics), Influenza B virus (immunology), Influenza B virus (isolation & purification), Influenza, Human (epidemiology), Influenza, Human (virology), Molecular Sequence Data, Mutation, Missense, Neuraminidase (chemistry), Neuraminidase (genetics), Phylogeny, Quebec (epidemiology), Sequence Analysis, Sequence Homology, Viral Nonstructural Proteins (chemistry), Viral Nonstructural Proteins (genetics).
- MESH :
- chemical , chemistry : Antigens, Viral, Hemagglutinin Glycoproteins, Influenza Virus, Neuraminidase, Viral Nonstructural Proteins.
- geographic , epidemiology : Quebec.
- epidemiology : Influenza, Human.
- genetics : Antigenic Variation, Antigens, Viral, Hemagglutinin Glycoproteins, Influenza Virus, Influenza B virus, Neuraminidase, Viral Nonstructural Proteins.
- chemical , immunology : Hemagglutinin Glycoproteins, Influenza Virus, Influenza B virus.
- isolation & purification : Influenza B virus.
- virology : Influenza, Human.
- Evolution, Molecular, Hemagglutination Inhibition Tests, Humans, Molecular Sequence Data, Mutation, Missense, Phylogeny, Sequence Analysis, Sequence Homology.
Abstract
After 2 minor winter seasons, influenza B viruses were predominantly isolated in the Province of Quebec, Canada, during the 2000-2001 season representing 74% of laboratory-confirmed influenza viruses. We performed an antigenic study of the hemagglutinin (HA) protein and a molecular characterization of the HA1 region, nonstructural-1 (NS1) and neuraminidase (NA)/NB genes of 20 influenza B strains isolated in the Province of Quebec during the 1998-2001 period. Our isolates were compared to recent vaccine strains (B/Harbin/7/94 in 1998-1999, B/Yamanashi/166/98 in 1999-2000 and 2000-2001, and B/Sichuan/379/99 in 2001-2002). The hemagglutination inhibition (HI) test revealed that all isolates were different from B/Harbin/7/94 and were more related to the 2 other vaccine strains although precise identification was often impossible. Molecular analysis of the HA1 gene revealed that both B/Yamanashi/166/98-like and B/Sichuan/379/99-like isolates co-circulated during the 1998-1999 season whereas isolates from the 2 subsequent years were more related to B/Sichuan/379/99. Most isolates (8/9) of the 2000-2001 season contained a N126D substitution recently associated with altered antigenicity in recent influenza B/Yamagata/16/88-related viruses. Although the HA1 and NS1 protein sequences of viruses isolated during the 1998-1999 season were clearly different from those of the respective vaccine strain (B/Harbin/7/94), the NA protein sequence of those isolates was slightly more related to B/Harbin/7/94 than B/Yamanashi/166/98 suggesting distinct patterns of evolution for these genes. This study confirms the importance of a detailed molecular analysis for understanding the evolution of influenza B viruses.
DOI: 10.1023/a:1025768308631
PubMed: 14501190
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Evolution of surface and nonstructural-1 genes of influenza B viruses isolated in the Province of Québec, Canada, during the 1998-2001 period.</title><author><name sortKey="Abed, Yacine" sort="Abed, Yacine" uniqKey="Abed Y" first="Yacine" last="Abed">Yacine Abed</name><affiliation wicri:level="1"><nlm:affiliation>Infectious Disease Research Center, Centre Hospitalier Universitaire de Québec, Québec City, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Infectious Disease Research Center, Centre Hospitalier Universitaire de Québec, Québec City</wicri:regionArea><wicri:noRegion>Québec City</wicri:noRegion></affiliation></author><author><name sortKey="Coulthart, Michael B" sort="Coulthart, Michael B" uniqKey="Coulthart M" first="Michael B" last="Coulthart">Michael B. Coulthart</name></author><author><name sortKey="Li, Yan" sort="Li, Yan" uniqKey="Li Y" first="Yan" last="Li">Yan Li</name></author><author><name sortKey="Boivin, Guy" sort="Boivin, Guy" uniqKey="Boivin G" first="Guy" last="Boivin">Guy Boivin</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2003">2003</date><idno type="RBID">pubmed:14501190</idno><idno type="pmid">14501190</idno><idno type="doi">10.1023/a:1025768308631</idno><idno type="wicri:Area/Main/Corpus">000A15</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000A15</idno><idno type="wicri:Area/Main/Curation">000A15</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000A15</idno><idno type="wicri:Area/Main/Exploration">000A15</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Evolution of surface and nonstructural-1 genes of influenza B viruses isolated in the Province of Québec, Canada, during the 1998-2001 period.</title><author><name sortKey="Abed, Yacine" sort="Abed, Yacine" uniqKey="Abed Y" first="Yacine" last="Abed">Yacine Abed</name><affiliation wicri:level="1"><nlm:affiliation>Infectious Disease Research Center, Centre Hospitalier Universitaire de Québec, Québec City, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Infectious Disease Research Center, Centre Hospitalier Universitaire de Québec, Québec City</wicri:regionArea><wicri:noRegion>Québec City</wicri:noRegion></affiliation></author><author><name sortKey="Coulthart, Michael B" sort="Coulthart, Michael B" uniqKey="Coulthart M" first="Michael B" last="Coulthart">Michael B. Coulthart</name></author><author><name sortKey="Li, Yan" sort="Li, Yan" uniqKey="Li Y" first="Yan" last="Li">Yan Li</name></author><author><name sortKey="Boivin, Guy" sort="Boivin, Guy" uniqKey="Boivin G" first="Guy" last="Boivin">Guy Boivin</name></author></analytic><series><title level="j">Virus genes</title><idno type="ISSN">0920-8569</idno><imprint><date when="2003" type="published">2003</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antigenic Variation (genetics)</term><term>Antigens, Viral (chemistry)</term><term>Antigens, Viral (genetics)</term><term>Evolution, Molecular</term><term>Hemagglutination Inhibition Tests</term><term>Hemagglutinin Glycoproteins, Influenza Virus (chemistry)</term><term>Hemagglutinin Glycoproteins, Influenza Virus (genetics)</term><term>Hemagglutinin Glycoproteins, Influenza Virus (immunology)</term><term>Humans</term><term>Influenza B virus (genetics)</term><term>Influenza B virus (immunology)</term><term>Influenza B virus (isolation & purification)</term><term>Influenza, Human (epidemiology)</term><term>Influenza, Human (virology)</term><term>Molecular Sequence Data</term><term>Mutation, Missense</term><term>Neuraminidase (chemistry)</term><term>Neuraminidase (genetics)</term><term>Phylogeny</term><term>Quebec (epidemiology)</term><term>Sequence Analysis</term><term>Sequence Homology</term><term>Viral Nonstructural Proteins (chemistry)</term><term>Viral Nonstructural Proteins (genetics)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Analyse de séquence</term><term>Antigènes viraux ()</term><term>Antigènes viraux (génétique)</term><term>Données de séquences moléculaires</term><term>Glycoprotéine hémagglutinine du virus influenza ()</term><term>Glycoprotéine hémagglutinine du virus influenza (génétique)</term><term>Glycoprotéine hémagglutinine du virus influenza (immunologie)</term><term>Grippe humaine (virologie)</term><term>Grippe humaine (épidémiologie)</term><term>Humains</term><term>Mutation faux-sens</term><term>Phylogénie</term><term>Protéines virales non structurales ()</term><term>Protéines virales non structurales (génétique)</term><term>Québec (épidémiologie)</term><term>Sialidase ()</term><term>Sialidase (génétique)</term><term>Similitude de séquences</term><term>Tests d'inhibition de l'hémagglutination</term><term>Variation des antigènes (génétique)</term><term>Virus influenza B (génétique)</term><term>Virus influenza B (immunologie)</term><term>Virus influenza B (isolement et purification)</term><term>Évolution moléculaire</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Antigens, Viral</term><term>Hemagglutinin Glycoproteins, Influenza Virus</term><term>Neuraminidase</term><term>Viral Nonstructural Proteins</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Quebec</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Antigenic Variation</term><term>Antigens, Viral</term><term>Hemagglutinin Glycoproteins, Influenza Virus</term><term>Influenza B virus</term><term>Neuraminidase</term><term>Viral Nonstructural Proteins</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Antigènes viraux</term><term>Glycoprotéine hémagglutinine du virus influenza</term><term>Protéines virales non structurales</term><term>Sialidase</term><term>Variation des antigènes</term><term>Virus influenza B</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Glycoprotéine hémagglutinine du virus influenza</term><term>Virus influenza B</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Hemagglutinin Glycoproteins, Influenza Virus</term><term>Influenza B virus</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Influenza B virus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Virus influenza B</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Grippe humaine</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Grippe humaine</term><term>Québec</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Evolution, Molecular</term><term>Hemagglutination Inhibition Tests</term><term>Humans</term><term>Molecular Sequence Data</term><term>Mutation, Missense</term><term>Phylogeny</term><term>Sequence Analysis</term><term>Sequence Homology</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Analyse de séquence</term><term>Antigènes viraux</term><term>Données de séquences moléculaires</term><term>Glycoprotéine hémagglutinine du virus influenza</term><term>Humains</term><term>Mutation faux-sens</term><term>Phylogénie</term><term>Protéines virales non structurales</term><term>Sialidase</term><term>Similitude de séquences</term><term>Tests d'inhibition de l'hémagglutination</term><term>Évolution moléculaire</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">After 2 minor winter seasons, influenza B viruses were predominantly isolated in the Province of Quebec, Canada, during the 2000-2001 season representing 74% of laboratory-confirmed influenza viruses. We performed an antigenic study of the hemagglutinin (HA) protein and a molecular characterization of the HA1 region, nonstructural-1 (NS1) and neuraminidase (NA)/NB genes of 20 influenza B strains isolated in the Province of Quebec during the 1998-2001 period. Our isolates were compared to recent vaccine strains (B/Harbin/7/94 in 1998-1999, B/Yamanashi/166/98 in 1999-2000 and 2000-2001, and B/Sichuan/379/99 in 2001-2002). The hemagglutination inhibition (HI) test revealed that all isolates were different from B/Harbin/7/94 and were more related to the 2 other vaccine strains although precise identification was often impossible. Molecular analysis of the HA1 gene revealed that both B/Yamanashi/166/98-like and B/Sichuan/379/99-like isolates co-circulated during the 1998-1999 season whereas isolates from the 2 subsequent years were more related to B/Sichuan/379/99. Most isolates (8/9) of the 2000-2001 season contained a N126D substitution recently associated with altered antigenicity in recent influenza B/Yamagata/16/88-related viruses. Although the HA1 and NS1 protein sequences of viruses isolated during the 1998-1999 season were clearly different from those of the respective vaccine strain (B/Harbin/7/94), the NA protein sequence of those isolates was slightly more related to B/Harbin/7/94 than B/Yamanashi/166/98 suggesting distinct patterns of evolution for these genes. This study confirms the importance of a detailed molecular analysis for understanding the evolution of influenza B viruses.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">14501190</PMID><DateCompleted><Year>2003</Year><Month>12</Month><Day>11</Day></DateCompleted><DateRevised><Year>2019</Year><Month>10</Month><Day>26</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0920-8569</ISSN><JournalIssue CitedMedium="Print"><Volume>27</Volume><Issue>2</Issue><PubDate><Year>2003</Year><Month>Oct</Month></PubDate></JournalIssue><Title>Virus genes</Title><ISOAbbreviation>Virus Genes</ISOAbbreviation></Journal><ArticleTitle>Evolution of surface and nonstructural-1 genes of influenza B viruses isolated in the Province of Québec, Canada, during the 1998-2001 period.</ArticleTitle><Pagination><MedlinePgn>125-35</MedlinePgn></Pagination><Abstract><AbstractText>After 2 minor winter seasons, influenza B viruses were predominantly isolated in the Province of Quebec, Canada, during the 2000-2001 season representing 74% of laboratory-confirmed influenza viruses. We performed an antigenic study of the hemagglutinin (HA) protein and a molecular characterization of the HA1 region, nonstructural-1 (NS1) and neuraminidase (NA)/NB genes of 20 influenza B strains isolated in the Province of Quebec during the 1998-2001 period. Our isolates were compared to recent vaccine strains (B/Harbin/7/94 in 1998-1999, B/Yamanashi/166/98 in 1999-2000 and 2000-2001, and B/Sichuan/379/99 in 2001-2002). The hemagglutination inhibition (HI) test revealed that all isolates were different from B/Harbin/7/94 and were more related to the 2 other vaccine strains although precise identification was often impossible. Molecular analysis of the HA1 gene revealed that both B/Yamanashi/166/98-like and B/Sichuan/379/99-like isolates co-circulated during the 1998-1999 season whereas isolates from the 2 subsequent years were more related to B/Sichuan/379/99. Most isolates (8/9) of the 2000-2001 season contained a N126D substitution recently associated with altered antigenicity in recent influenza B/Yamagata/16/88-related viruses. Although the HA1 and NS1 protein sequences of viruses isolated during the 1998-1999 season were clearly different from those of the respective vaccine strain (B/Harbin/7/94), the NA protein sequence of those isolates was slightly more related to B/Harbin/7/94 than B/Yamanashi/166/98 suggesting distinct patterns of evolution for these genes. This study confirms the importance of a detailed molecular analysis for understanding the evolution of influenza B viruses.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Abed</LastName><ForeName>Yacine</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Infectious Disease Research Center, Centre Hospitalier Universitaire de Québec, Québec City, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Coulthart</LastName><ForeName>Michael B</ForeName><Initials>MB</Initials></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Yan</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Boivin</LastName><ForeName>Guy</ForeName><Initials>G</Initials></Author></AuthorList><Language>eng</Language><DataBankList CompleteYN="Y"><DataBank><DataBankName>GENBANK</DataBankName><AccessionNumberList><AccessionNumber>AJ419108</AccessionNumber><AccessionNumber>AJ419109</AccessionNumber><AccessionNumber>AJ419110</AccessionNumber><AccessionNumber>AJ419111</AccessionNumber><AccessionNumber>AJ419112</AccessionNumber><AccessionNumber>AJ419113</AccessionNumber><AccessionNumber>AJ419114</AccessionNumber><AccessionNumber>AJ419115</AccessionNumber><AccessionNumber>AJ419116</AccessionNumber><AccessionNumber>AJ419117</AccessionNumber><AccessionNumber>AJ419118</AccessionNumber><AccessionNumber>AJ419119</AccessionNumber><AccessionNumber>AJ419120</AccessionNumber><AccessionNumber>AJ419121</AccessionNumber><AccessionNumber>AJ419122</AccessionNumber><AccessionNumber>AJ419123</AccessionNumber><AccessionNumber>AJ419124</AccessionNumber><AccessionNumber>AJ419125</AccessionNumber><AccessionNumber>AJ419126</AccessionNumber><AccessionNumber>AJ419127</AccessionNumber><AccessionNumber>AJ419574</AccessionNumber><AccessionNumber>AJ419575</AccessionNumber><AccessionNumber>AJ419576</AccessionNumber><AccessionNumber>AJ419577</AccessionNumber><AccessionNumber>AJ419578</AccessionNumber><AccessionNumber>AJ419579</AccessionNumber><AccessionNumber>AJ419580</AccessionNumber><AccessionNumber>AJ419581</AccessionNumber><AccessionNumber>AJ419582</AccessionNumber><AccessionNumber>AJ419583</AccessionNumber><AccessionNumber>AJ419584</AccessionNumber><AccessionNumber>AJ419585</AccessionNumber><AccessionNumber>AJ419586</AccessionNumber><AccessionNumber>AJ419587</AccessionNumber><AccessionNumber>AJ419588</AccessionNumber><AccessionNumber>AJ419589</AccessionNumber><AccessionNumber>AJ419590</AccessionNumber><AccessionNumber>AJ419591</AccessionNumber><AccessionNumber>AJ419592</AccessionNumber><AccessionNumber>AJ419593</AccessionNumber></AccessionNumberList></DataBank></DataBankList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Virus Genes</MedlineTA><NlmUniqueID>8803967</NlmUniqueID><ISSNLinking>0920-8569</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000956">Antigens, Viral</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D019267">Hemagglutinin Glycoproteins, Influenza Virus</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D017361">Viral Nonstructural Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.2.1.18</RegistryNumber><NameOfSubstance UI="D009439">Neuraminidase</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000940" MajorTopicYN="N">Antigenic Variation</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000956" MajorTopicYN="N">Antigens, Viral</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D019143" MajorTopicYN="Y">Evolution, Molecular</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006385" MajorTopicYN="N">Hemagglutination Inhibition Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019267" MajorTopicYN="N">Hemagglutinin Glycoproteins, Influenza Virus</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009981" MajorTopicYN="N">Influenza B virus</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName><QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008969" MajorTopicYN="N">Molecular Sequence Data</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020125" MajorTopicYN="N">Mutation, Missense</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009439" MajorTopicYN="N">Neuraminidase</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010802" MajorTopicYN="N">Phylogeny</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011792" MajorTopicYN="N" Type="Geographic">Quebec</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017421" MajorTopicYN="N">Sequence Analysis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017385" MajorTopicYN="N">Sequence Homology</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017361" MajorTopicYN="N">Viral Nonstructural Proteins</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2003</Year><Month>9</Month><Day>23</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2003</Year><Month>12</Month><Day>12</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2003</Year><Month>9</Month><Day>23</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">14501190</ArticleId><ArticleId IdType="pii">5142893</ArticleId><ArticleId IdType="doi">10.1023/a:1025768308631</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Virology. 1985 Jun;143(2):583-94</Citation><ArticleIdList><ArticleId IdType="pubmed">2414911</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 1982 Nov;79(22):6817-21</Citation><ArticleIdList><ArticleId IdType="pubmed">6294654</ArticleId></ArticleIdList></Reference><Reference><Citation>Arch Virol. 1998;143(8):1569-83</Citation><ArticleIdList><ArticleId IdType="pubmed">9739335</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 1999 Sep;73(9):7343-8</Citation><ArticleIdList><ArticleId IdType="pubmed">10438823</ArticleId></ArticleIdList></Reference><Reference><Citation>Epidemiol Infect. 1993 Dec;111(3):539-46</Citation><ArticleIdList><ArticleId IdType="pubmed">8270013</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Diagn Virol. 1996 Jun;6(1):63-71</Citation><ArticleIdList><ArticleId IdType="pubmed">15566891</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 1990 Mar;175(1):59-68</Citation><ArticleIdList><ArticleId IdType="pubmed">2309452</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 1990 May;87(10):3884-8</Citation><ArticleIdList><ArticleId IdType="pubmed">2378639</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Microbiol. 2002 Aug;40(8):3068-70</Citation><ArticleIdList><ArticleId IdType="pubmed">12149383</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 1981 Jan 29;289(5796):373-8</Citation><ArticleIdList><ArticleId IdType="pubmed">6162101</ArticleId></ArticleIdList></Reference><Reference><Citation>J Gen Virol. 1992 Oct;73 ( Pt 10):2737-42</Citation><ArticleIdList><ArticleId IdType="pubmed">1402807</ArticleId></ArticleIdList></Reference><Reference><Citation>Eur J Epidemiol. 1994 Aug;10(4):465-6</Citation><ArticleIdList><ArticleId IdType="pubmed">7843357</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 1997 Dec 15;25(24):4876-82</Citation><ArticleIdList><ArticleId IdType="pubmed">9396791</ArticleId></ArticleIdList></Reference><Reference><Citation>J Med Virol. 1999 Oct;59(2):208-14</Citation><ArticleIdList><ArticleId IdType="pubmed">10459158</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Biol Evol. 1999 Nov;16(11):1457-65</Citation><ArticleIdList><ArticleId IdType="pubmed">10555276</ArticleId></ArticleIdList></Reference><Reference><Citation>Eur J Epidemiol. 1994 Aug;10(4):467-70</Citation><ArticleIdList><ArticleId IdType="pubmed">7843358</ArticleId></ArticleIdList></Reference><Reference><Citation>Virus Res. 2001 Sep;77(1):89-96</Citation><ArticleIdList><ArticleId IdType="pubmed">11451491</ArticleId></ArticleIdList></Reference><Reference><Citation>J Med Virol. 2001 Dec;65(4):745-50</Citation><ArticleIdList><ArticleId IdType="pubmed">11745940</ArticleId></ArticleIdList></Reference><Reference><Citation>J Med Virol. 2002 Aug;67(4):589-95</Citation><ArticleIdList><ArticleId IdType="pubmed">12116009</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 1999 May;73(5):4413-26</Citation><ArticleIdList><ArticleId IdType="pubmed">10196339</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 1993 Feb;192(2):683-6</Citation><ArticleIdList><ArticleId IdType="pubmed">8421908</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 1988 Mar;163(1):112-22</Citation><ArticleIdList><ArticleId IdType="pubmed">3267218</ArticleId></ArticleIdList></Reference><Reference><Citation>Virus Genes. 1997;14(3):181-5</Citation><ArticleIdList><ArticleId IdType="pubmed">9311562</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 1984 Dec;52(3):919-27</Citation><ArticleIdList><ArticleId IdType="pubmed">6208383</ArticleId></ArticleIdList></Reference><Reference><Citation>J Infect Dis. 2000 Apr;181(4):1471-4</Citation><ArticleIdList><ArticleId IdType="pubmed">10762579</ArticleId></ArticleIdList></Reference><Reference><Citation>Arch Virol. 1999;144(10):1881-91</Citation><ArticleIdList><ArticleId IdType="pubmed">10550663</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 1995 Feb 1;206(2):787-95</Citation><ArticleIdList><ArticleId IdType="pubmed">7856092</ArticleId></ArticleIdList></Reference><Reference><Citation>Arch Virol. 2001;146(9):1667-79</Citation><ArticleIdList><ArticleId IdType="pubmed">11699954</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 1998 Sep 12;352(9131):873-5</Citation><ArticleIdList><ArticleId IdType="pubmed">9742980</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>Canada</li></country></list><tree><noCountry><name sortKey="Boivin, Guy" sort="Boivin, Guy" uniqKey="Boivin G" first="Guy" last="Boivin">Guy Boivin</name><name sortKey="Coulthart, Michael B" sort="Coulthart, Michael B" uniqKey="Coulthart M" first="Michael B" last="Coulthart">Michael B. Coulthart</name><name sortKey="Li, Yan" sort="Li, Yan" uniqKey="Li Y" first="Yan" last="Li">Yan Li</name></noCountry><country name="Canada"><noRegion><name sortKey="Abed, Yacine" sort="Abed, Yacine" uniqKey="Abed Y" first="Yacine" last="Abed">Yacine Abed</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/GrippeCanadaV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000946 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000946 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= GrippeCanadaV3
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:14501190
|texte= Evolution of surface and nonstructural-1 genes of influenza B viruses isolated in the Province of Québec, Canada, during the 1998-2001 period.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:14501190" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a GrippeCanadaV3
| This area was generated with Dilib version V0.6.35. |  |